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Trace Element·Vitamins & Minerals
Total Parenteral Nutrition (TPN) additive, Keshan disease, thyroid dysfunction support
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Max Dose
400 mcg/day
Caution: Toxicity
GARLIC BREATH
High risk: Hair Loss
TOXICITY SIGN
Thyroid
COFACTOR
Avoid / Cautions
Selenosis.
Overview
Trace mineral essential for glutathione peroxidase (antioxidant defense) and thyroid hormone conversion. Extremely toxic in overdose.
Clinical Focus
Selenium has a narrow therapeutic window: deficiency replacement is reasonable, but chronic excess causes selenosis with hair/nail changes, gastrointestinal symptoms, neuropathy, and garlic odour.
Bottom Line
Selenium is an essential trace element for thyroid function and antioxidant defence, but has a narrow therapeutic window with toxicity (selenosis) causing hair loss, GI symptoms, and neuropathy.
Brand Names
Various OTC
Oral Routes
Tablets.
Prescribing & PBS
Over The Counter (OTC).
Primary
Total Parenteral Nutrition (TPN) additive, Keshan disease, thyroid dysfunction support.
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