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Prandial Insulin·Endocrinology - Insulins & Injectables
Type 1 and Type 2 Diabetes
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Max Dose
Titrated
Caution: Onset
10-15 mins
Timing
WITH MEALS
High risk: Hypoglycemia
HIGH RISK
Avoid / Cautions
Active hypoglycemia. Pregnancy Category B3 (Aspart/Lispro have Category A status, making them preferred in pregnancy).
Overview
Ultra-rapid-acting mealtime insulin. Functionally equivalent to Aspart and Lispro, providing immediate post-prandial glucose control.
Clinical Focus
Must be injected just before or within 20 mins of starting a meal.
Bottom Line
Insulin glulisine is a rapid-acting mealtime insulin alternative to aspart and lispro, but offers no clear advantage and is less widely prescribed.
Brand Names
Apidra
Parenteral
Pre-filled pens for SC injection (100 U/mL). Clear solution.
Prescribing & PBS
Authority Required (PBS).
Primary
Type 1 and Type 2 Diabetes.
Clinical Place
Interchangeable rapid-acting analogue. Choice usually depends on endocrinologist preference or state contracts.
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