Loading…
5-Alpha Reductase Inhibitor·Urology
BPH to reduce symptom progression and surgical risk
No source link confirmed for this record yet. Its own source notes are under Additional.
Max Dose
500 mcg/day
Caution: Half-life
5 WEEKS
High risk: Teratogenic
CATEGORY X
Caution: Onset
3-6 MONTHS
Avoid / Cautions
Women, children. Pregnant women MUST NOT touch leaking capsules (Category X).
Overview
Dual 5-Alpha Reductase Inhibitor. More potent than Finasteride, blocking both Type I and Type II enzymes. Profoundly drops DHT levels.
Clinical Focus
Has a massive 5-week half-life. Patients cannot donate blood for 6 months after stopping due to teratogenic risk to pregnant recipients.
Bottom Line
Dutasteride is a more potent dual 5-alpha reductase inhibitor than finasteride for BPH, but has a very long half-life (5 weeks) and the same sexual side-effect profile.
Brand Names
Avodart, Duodart (combo with Tamsulosin)
Oral Routes
Soft gelatin capsules (500 mcg).
Prescribing & PBS
Authority Required (PBS).
Primary
BPH to reduce symptom progression and surgical risk.
Clinical Place
Often preferred over finasteride as combo therapy (Duodart) for aggressive BPH management.
No calculator, monitoring schedule or factsheet is linked to this medicine page yet.