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Presentation comparison
UrgentCovers bipolar, trauma-related, personality, neurodevelopmental, substance-related, and neurological causes.
1 of 8 diagnoses compared
| CriteriaComparison detail | ADHDUrgent |
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Shifts are reactive, brief, and relationship-linked rather than sustained episodic elevation with reduced need for sleep.
Clinical reference — not validated decision support. Review before use.
| Bipolar disorderUrgentNot selected |
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| CyclothymiaUrgentNot selected |
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| Complex PTSDUrgentNot selected |
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| Autism with overloadUrgentNot selected |
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| Substance intoxication or withdrawalEmergencyNot selected |
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| Frontal lobe syndromeUrgentNot selected |
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| Why it fits | Chronic irritability, low frustration tolerance, impulsive outbursts, emotional reactivity since youth | Rapid affective shifts around perceived rejection, abandonment, invalidation | Distinct episodes of elevated/expansive/irritable mood with altered sleep, activity, confidence | Chronic oscillation between low and activated states falling short of major episodes | Affective storms linked to trauma reminders, shame, threat, attachment rupture | Abrupt dysregulation from sensory overload, change, uncertainty, social demand | Mood swings around intoxication, rebound, or withdrawal periods | New lability, disinhibition, apathy, especially later in life |
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| What argues against | Applies to the whole presentationReview locally. | |||||||
| Must-not-miss | Substance misuse, accidents, educational/occupational collapse | Self-harm, dissociation, acute suicide risk, escalating interpersonal violence | Mixed state, psychosis, disinhibition, postpartum relapse | Escalation into bipolar I/II, antidepressant-induced switch | ||||
| Bedside question | Applies to the whole presentationShifts are reactive, brief, and relationship-linked rather than sustained episodic elevation with reduced need for sleep. | |||||||
| Immediate action | Applies to the whole presentationStabilise and reassess. | |||||||
| Investigations | Applies to the whole presentationGuided by presentation. | |||||||
| Mimics / overlap | Applies to the whole presentationReview overlap locally. | |||||||
Scroll horizontally to review more candidate differentials. Clinical reference — not validated decision support. Review before use.
Review locally.
Shifts are reactive, brief, and relationship-linked rather than sustained episodic elevation with reduced need for sleep.
Stabilise and reassess.
Guided by presentation.
Review overlap locally.
Chronic irritability, low frustration tolerance, impulsive outbursts, emotional reactivity since youth
Substance misuse, accidents, educational/occupational collapse
Create a concise comparison summary for documentation or handoff.
Source pending review
v10 | Local content only
Last updated: Pending review
Open a selected differential to review its clinical record.
Based on current selection
Safety first. Act early.
Create a concise comparison summary for documentation or handoff.
Source pending review
v10 | Local content only
Last updated: Pending review
| Catatonic regression, self-injury, exploitation risk |
| Alcohol/benzo withdrawal, stimulant crash suicidality, aggression, delirium |
| Rapid decline, seizure, focal neurology, tumour, delirium |